BioTek EL406 Washer Dispenser

The EL406 Combination Washer Dispenser offers fast, full plate washing along with three reagent dispensers in one, compact instrument. Its multiple capabilities include washing and dispensing for standard assays, plus biomagnetic separation and vacuum filtration protocols. The Dual-Action™ manifold optimizes washing for loosely adherent cell monolayers, while the patented Ultrasonic Advantage™ helps prevent blockages in the manifold tubes before washing, to reduce assay failure. Syringe pump and peristaltic pump dispensers each offer unique advantages, and the EL406 offers both, along with superior plate washing, on a single platform – making the EL406 a workhorse for your laboratory.

BioTek EL406 Washer Dispenser

The EL406 Combination Washer Dispenser offers fast, full plate washing along with three reagent dispensers in one, compact instrument. Its multiple capabilities include washing and dispensing for standard assays, plus biomagnetic separation and vacuum filtration protocols. The Dual-Action™ manifold optimizes washing for loosely adherent cell monolayers, while the patented Ultrasonic Advantage™ helps prevent blockages in the manifold tubes before washing, to reduce assay failure. Syringe pump and peristaltic pump dispensers each offer unique advantages, and the EL406 offers both, along with superior plate washing, on a single platform – making the EL406 a workhorse for your laboratory.


General

Microplate types 96-, 384- and 1536-well
Low profile and standard height
Solid and filter bottom (option)
Onboard software Create, edit or run multiple protocols
Software (computer control) LHC2 Software
LHC2 Secure for 21 CFR Part 11 compliance (option)
SiLA Compliant driver (option)
Separation Biomagnetic separation, vacuum filtration (optional)
Shaking Programmable up to 60 minutes
Slow, medium, fast or variable
Soaking Programmable up to 60 minutes
Ultrasonic Advantage™ Standard on most configurations
Automation BioStack and 3rd party automation compatible
BioSpa 8 Automated Incubator compatible
Microplate types 96-, 384- and 1536-well
Low profile and standard height
Solid and filter bottom (option)
Onboard software Create, edit or run multiple protocols
Software (computer control) LHC2 Software
LHC2 Secure for 21 CFR Part 11 compliance (option)
SiLA Compliant driver (option)
Separation Biomagnetic separation, vacuum filtration (optional)
Shaking Programmable up to 60 minutes
Slow, medium, fast or variable
Soaking Programmable up to 60 minutes
Ultrasonic Advantage™ Standard on most configurations
Automation BioStack and 3rd party automation compatible
BioSpa 8 Automated Incubator compatible

Washing

Manifold types 96-well washing: 96-tube manifold - straight dispense tubes
96- and 384-well washing: 96-tube Dual-Action manifold - 20° angled dispense tubes
384-well washing (fast): 192-tube Dual-Action manifold - 7° angled dispense tubes
1536-well washing: Two 32-tube dispense manifolds - 7° angled dispense tubes
Volume range 3 - 3,000 µL/well in 1 µL increments
Wash cycles 1 - 250
Buffer/reagent selection Auto switching module for up to 4 buffers (option)
Supply bottle 4 L or 10 L (optional)
Dispense accuracy +3%
Dispense precision <3% CV (model dependent)
Residual volume <2 µL/well
Wash speed 96 wells, 300 µL/well, 96-tube manifold: 13 seconds
384 wells, 100 µL/well, 192-tube manifold: 17 seconds
1536 wells, 10 µL/wells, two 32-tube manifolds: 36 seconds
Flow rates High flow to low flow
Optimized rates for cell assays
Sterilization Chemical
Vacuum range for filtration Selectable: 0 to -380 mmHg (final at 30s)
Filtration time: 5 - 999 seconds
Manifold types 96-well washing: 96-tube manifold - straight dispense tubes
96- and 384-well washing: 96-tube Dual-Action manifold - 20° angled dispense tubes
384-well washing (fast): 192-tube Dual-Action manifold - 7° angled dispense tubes
1536-well washing: Two 32-tube dispense manifolds - 7° angled dispense tubes
Volume range 3 - 3,000 µL/well in 1 µL increments
Wash cycles 1 - 250
Buffer/reagent selection Auto switching module for up to 4 buffers (option)
Supply bottle 4 L or 10 L (optional)
Dispense accuracy +3%
Dispense precision <3% CV (model dependent)
Residual volume <2 µL/well
Wash speed 96 wells, 300 µL/well, 96-tube manifold: 13 seconds
384 wells, 100 µL/well, 192-tube manifold: 17 seconds
1536 wells, 10 µL/wells, two 32-tube manifolds: 36 seconds
Flow rates High flow to low flow
Optimized rates for cell assays
Sterilization Chemical
Vacuum range for filtration Selectable: 0 to -380 mmHg (final at 30s)
Filtration time: 5 - 999 seconds

Dispensing - Peristaltic pump (Multi-Channel)

Manifold types 8-tip (1 x 8) cassette with plastic, 316 SS tubes or sapphire jeweled 316 SS tubes
Fluid delivery 1 peristaltic pump
Dispense speed 96 wells, 10 µL /well: 8 seconds
384 wells, 5 µL /well: 12 seconds
1536 wells, 1 µL /well: 27 seconds
Volume range 500 nL - 3,000 µL/well, selectable in 1 µL increments
Flow rates User programmable rates from high to low
Optimized rates for cell assays
Dispense performance 1 µL cassette:
Recommended Volume Range: 1 - 50 µL
Dispense Accuracy: +5% at 1 µL
Dispense Precision: <5% CV at 1 µL
<10% CV at 500 nL
Minimum Prime Volume: 1.20 mL
5 µL cassette:
Recommended Volume Range: 5 - 2,500 µL
Dispense Accuracy: +2.0% at 5 µL
Dispense Precision: <2.5% CV at 5 µL
Minimum Prime Volume: 4.23 mL
10 µL cassette:
Recommended Volume Range: 10 - 3,000 µL
Dispense Accuracy: +2.0% at 10 µL
Dispense Precision: <2.0% CV at 10 µL
Minimum Prime Volume: 7.36 mL
Recommended cassette replacement interval 1 µL Cassette: 1,000 384-well microplates at 5 µL well
5 µL Cassette: 1,000 96-well microplates at 50 µL well
10 µL Cassette: 1,000 96-well microplates at 100 µL well
Sterilization Autoclave, chemical
Manifold types 8-tip (1 x 8) cassette with plastic, 316 SS tubes or sapphire jeweled 316 SS tubes
Fluid delivery 1 peristaltic pump
Dispense speed 96 wells, 10 µL /well: 8 seconds
384 wells, 5 µL /well: 12 seconds
1536 wells, 1 µL /well: 27 seconds
Volume range 500 nL - 3,000 µL/well, selectable in 1 µL increments
Flow rates User programmable rates from high to low
Optimized rates for cell assays
Dispense performance 1 µL cassette:
Recommended Volume Range: 1 - 50 µL
Dispense Accuracy: +5% at 1 µL
Dispense Precision: <5% CV at 1 µL
<10% CV at 500 nL
Minimum Prime Volume: 1.20 mL
5 µL cassette:
Recommended Volume Range: 5 - 2,500 µL
Dispense Accuracy: +2.0% at 5 µL
Dispense Precision: <2.5% CV at 5 µL
Minimum Prime Volume: 4.23 mL
10 µL cassette:
Recommended Volume Range: 10 - 3,000 µL
Dispense Accuracy: +2.0% at 10 µL
Dispense Precision: <2.0% CV at 10 µL
Minimum Prime Volume: 7.36 mL
Recommended cassette replacement interval 1 µL Cassette: 1,000 384-well microplates at 5 µL well
5 µL Cassette: 1,000 96-well microplates at 50 µL well
10 µL Cassette: 1,000 96-well microplates at 100 µL well
Sterilization Autoclave, chemical

Dispensing - Syringe pump

Manifold types 96-well dispensing:
One 16-tube (2 x 8) manifold - 316 SS tubes
96-/384-well dispensing:
Two 16-tube (1 x 16) manifolds - 316 SS tubes
1536-well dispensing:
Two 32-tube (1 x 32) manifolds - sapphire jeweled 316 SS or 316 stainless steel tubes
Fluid delivery Two positive displacement syringe drives
Dispense speed 20 µL /well, 96 wells, 1 x 16 tubes: 5.25 seconds
20 µL /well, 384 wells, 1 x 16 tubes: 14 seconds
3 µL /well 1536 wells, 2 x 32 tubes: 7 seconds
Volume range 3 - 3,000 µL/well, selectable in 1 µL increments
Minimum Prime Volume: 12 mL
Flow rates User programmable rates from high to low
Dispense accuracy +1 µL at 5 µL
+1 µL at 20 µL
+1% at 100 µL
Dispense precision <5% CV at 5 µL
<2.5% CV at 20 µL
<1% CV at 100 µL
Supply bottle 1 L or 2 L
Sterilization Chemical, autoclavable option
Manifold types 96-well dispensing:
One 16-tube (2 x 8) manifold - 316 SS tubes
96-/384-well dispensing:
Two 16-tube (1 x 16) manifolds - 316 SS tubes
1536-well dispensing:
Two 32-tube (1 x 32) manifolds - sapphire jeweled 316 SS or 316 stainless steel tubes
Fluid delivery Two positive displacement syringe drives
Dispense speed 20 µL /well, 96 wells, 1 x 16 tubes: 5.25 seconds
20 µL /well, 384 wells, 1 x 16 tubes: 14 seconds
3 µL /well 1536 wells, 2 x 32 tubes: 7 seconds
Volume range 3 - 3,000 µL/well, selectable in 1 µL increments
Minimum Prime Volume: 12 mL
Flow rates User programmable rates from high to low
Dispense accuracy +1 µL at 5 µL
+1 µL at 20 µL
+1% at 100 µL
Dispense precision <5% CV at 5 µL
<2.5% CV at 20 µL
<1% CV at 100 µL
Supply bottle 1 L or 2 L
Sterilization Chemical, autoclavable option

Physical Characteristics

Power 100 - 240 Volts AC. 50/60 Hz
Dimensions 16.5" W x 18" D x 12.5" H (42 x 46 x 32 cm)
Weight 32 lbs (14.5 kg)
Power 100 - 240 Volts AC. 50/60 Hz
Dimensions 16.5" W x 18" D x 12.5" H (42 x 46 x 32 cm)
Weight 32 lbs (14.5 kg)

Regulatory

Regulatory CE and TUV marked. ROHS compliant. In Vitro Diagnostic use models are available.

Configurations

Part #
1536-/ 384-/ 96-well 1536-/ 384-well 1536-well 384-/ 96-well 384-well 96-well 3 reagent disp. 2 reagent disp. 1 reagent disp.
406PSUB3SB
406PSUB3LB
406PSUB1SB
406PSUB1LB
406PSUB2SB
406PSUB2LB
406PSU0SB
406PSU0LB
406SNA0LB
406PSUB3
406PSUB1
406PUB3
406PUB1
406PSUB2
406PUB2
406PSNA4
406SNA4
406P4

 

EL406™ 1536-/384-/96-well Microplate Washer Dispenser Configurations
Feature Design
P 1-Reagent Dispense Module –
1 Peristaltic Pump
  • Autoclavable
  • 8-tip (1 x 8) cassette
  • Sapphire jeweled, steel or plastic tips
S 2-Reagent Dispense Module –
2 Syringe Pumps
  • Autoclavable
  • 2 16-tube (1 x 16) manifolds
  • Steel tubes
SNA 2-Reagent Dispense Module –
2 Syringe Pumps
  • Non-autoclavable
  • 1 16-tube (2 x 8) manifolds - except with P/N 406SNA0-LB
  • Steel tubes
U Wash Module – Ultrasonic Advantage™
B Wash Module – Automatic 4-Buffer Switching
1 Wash Module – 384-/96-well microplate washing
  • Dual-Action™
  • 96-tube (8 x 12) manifold
  • Steel tubes
2 Wash Module – faster 384-well microplate washing
  • Dual-Action™
  • 192-tube (16 x 12) manifold
  • Steel tubes
3 Wash Module – 384-/96-well microplate washing
  • Dual-Action™
  • Interchangeable 96-tube (384-/96- well washing) and 192-tube (faster 384-well washing) manifolds
  • Steel tubes
4 Wash Module – 96-well microplate washing
  • 96-tube (8 x 12) manifold
  • Steel tubes
SB Wash Module – 1536-well microplate washing and dispensing
  • 2 32-tube (1 x 32) dispense manifolds
  • Small bore, sapphire jeweled tubes
  • 128-tube (4 x 32) aspiration manifold
LB Wash Module – 1536-well microplate washing and dispensing
  • 2 32-tube (1 x 32) dispense manifolds
  • Large bore, steel tubes
  • 128-tube (4 x 32) aspiration manifold